Cartridge for storing biosample plates and use in automated data storage systems

ABSTRACT

In one embodiment, a method of using a biosample storage cartridge includes performing bioanalysis on one or more biosamples in one or more biosample plates in a holder of a biosample storage cartridge, the biosample storage cartridge having an enclosure having a same form factor as a data tape cartridge that is configured for use in an automated tape library, the holder being disposed in the enclosure, wherein the holder comprises a plurality of slots, each slot being configured to receive a biosample plate. In another embodiment, a computer program product for using a biosample storage cartridge, the computer program product including a computer readable storage medium having program instructions embodied therewith, the program instructions executable by an analytical system to cause the analytical system to perform the foregoing method.

BACKGROUND

Embodiments of the invention relate to analytical devices and systems,and more particularly, to a cartridge having internal slots for storingbiosample plates wherein the cartridge may be stored in the cartridgestorage slots of tape library systems and handled by the roboticmechanisms of the tape library systems.

Samples of biological matters are often analyzed in bio-assay processesto detect the presence of bacteria, viruses, cancer cells, and othersubstances of interest. The biological samples are typically placed onbiosample plates to be analyzed by a biological detection instrument.The detection instrument may record the analysis results of a biosampleon a data storage medium such as a computer memory, disk drive, magnetictape, or compact disk, which may include an identification tag tocorrelate the biosample with the analysis results.

High-performance computer data storage systems such as optical disc andmagnetic tape libraries possess the automation to facilitate thescanning and analysis of biosamples, and to tabulate the resultinganalysis data. For example, these systems may analyze the biosamplesusing magnetic tape read heads to detect magnetized nanoparticlesattached to the biosamples. The biosamples and analysis data may bestored in different locations following the analysis, which make itdifficult to correlate the biosamples with the corresponding data whenneeded. For a large number of biosamples and biosample plates, the taskof correlating the biosamples to their data becomes even more complex.It is desirable to exploit the use of automation functions available incomputer tape library systems to facilitate the correlation andmanagement of biosample plates and biosample analysis data.

SUMMARY

The disclosure relates to a biosample storage cartridge, as well asmethods and computer program products configured for the use thereof.

In one embodiment, a method of using a biosample storage cartridgeincludes performing bioanalysis on one or more biosamples in one or morebiosample plates in a holder of a biosample storage cartridge, thebiosample storage cartridge having an enclosure having a same formfactor as a data tape cartridge that is configured for use in anautomated tape library, the holder being disposed in the enclosure,wherein the holder comprises a plurality of slots, each slot beingconfigured to receive a biosample plate.

In another embodiment, a computer program product for using a biosamplestorage cartridge, the computer program product including a computerreadable storage medium having program instructions embodied therewith,the program instructions executable by an analytical system to cause theanalytical system to perform the foregoing method.

The details of the exemplary embodiments of the disclosure, both as toits structure and operation, are described below in the DetailedDescription section in reference to the accompanying drawings. The BriefSummary is intended to identify key features of the claimed subjectmatter, but it is not intended to be used to limit the scope of theclaimed subject matter.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 illustrates an exemplary cartridge for storing biosample plates,in accordance with an embodiment of the invention.

FIG. 2 illustrates a biosample storage cartridge with its cover openedto show the storage slots for holding biosample plates in the cartridge,in accordance with an embodiment of the invention.

FIG. 3 illustrates a cross-sectional side view of a biosample platestorage cartridge with the slots for holding biosample plates, inaccordance with an embodiment of the invention.

FIG. 4 illustrates a block diagram of a memory component and a wirelesscommunication interface, which may be part of a biosample plate storagecartridge, for storing and transferring information related to thecartridge, in accordance with an embodiment of the invention.

FIG. 5 illustrates an automated data storage tape library that may beused with the disclosed biosample plate storage cartridge, in accordancewith an embodiment of the invention.

FIG. 6 illustrates a block diagram of the functional components in adata storage tape drive that may be used for analyzing a biosample andstoring biosample identification and analysis data, in accordance withan embodiment of the invention.

FIG. 7 illustrates a block diagram of the functional components in acomputer, which may be incorporated into a data storage tape library anda cartridge memory to provide control and processing functions, inaccordance with an embodiment of the invention.

DETAILED DESCRIPTION

Embodiments of the disclosure relate to biosample cartridges thatinclude internal storage slots for holding biosample plates that may bescanned, analyzed, and handled by a computer tape drive and stored inthe cartridge storage slots of an automated tape library. The biosampleplates may contain biological samples that are written to byelectromagnetic tape heads. They may then be scanned and read from byanisotropic magneto-resistive (AMR), giant magnetoresistive (GMR) ortunnel magnetoresistive (TMR) read elements to detect the presence oftarget substances or micro-organisms in the biological samples. Thebiosample plates may have a width of 12.65 mm (½ inch), which is thewidth of commonly used magnetic data tapes. The biosample plate storagecartridge may have the same form factor as data tape cartridges used inautomated data storage libraries and thus may be conveniently accessed,manipulated, and processed by robotic mechanisms in these libraries. Thebiosample cartridge may be handled through the same libraryinternal-external mail slot as a tape cartridge. The same tapeautomation mechanisms and processes used in modern tape libraries may beused for long-term biological-archival storage of the biosamplescontained in the biosample cartridge.

The biosample storage cartridge may include a plate holder to retain aplurality of biosample plates in the cartridge when the cartridge ismoved, for example by a robotic picker in a tape library, as well aswhen the cartridge is in storage. The plate holder may have a pluralityof parallel storage slots for receiving the biosample plates, which maybe in the form of thin strips of glass or a similar material. Thebiosample plate storage cartridge is described in detail below withreference to FIGS. 1-3.

Referring to the drawings and in particular to FIG. 1, there isillustrated an exemplary biosample plate storage cartridge 100 in whicha plurality of slots may be provided to hold the biosample plates. Thebiosample plate storage cartridge 100 comprises an enclosure 101, whichmay include one or more parts. The cartridge 100 may have a movable sidedoor 102 that can be slid open, for example by a tape drive, to gainaccess to the interior space of the cartridge 100. The tape dive may beadapted to perform biosample analysis. In one embodiment, the biosampleplate storage cartridge 100 may comprise a top shell 101A and a bottomshell 101B wherein the top shell 101A is removably affixed to the bottomshell 101B by screws or other fasteners. Alternatively, the biosampleplate storage cartridge 100 may have a front, top, or rear door that ismovable to provide access to the interior space of the cartridge.

The biosample plate storage cartridge 100 may have the same size andexterior configuration as a magnetic tape storage cartridge based on LTO(Linear Tape Open) technology, the IBM TS1130 magnetic tape data storagecartridge, or the Oracle T10000 tape cartridge. In an alternateembodiment, older IBM single-reel tape cartridges could be used, such asthe 3480, 3490, and 3590 tape cartridges. In a data storage cartridge, adata storage media such as a magnetic tape, may be mounted on a tapereel and occupy the space inside the biosample storage cartridge 100rather than the biosample plates. Such a tape data storage cartridge maycomprise a cartridge brake release button to allow the tape reel tofreely rotate once the cartridge is loaded into a data storage drive.

The biosample plate storage cartridge 100 may further include one ormore cartridge memories 103 for storing identification information aboutthe biosample storage cartridge 100, data related to the biosampleplates, and analysis data associated with the biosamples stored in thebiosample storage cartridge 100. Each cartridge memory 103 may comprisea transponder having a wireless interface, which is retained in thecartridge 100, for example, by being encapsulated by the cartridge whenit is assembled. The encapsulation process is understood by those ofskill in the art as applied to a single cartridge memory.

FIG. 2 illustrates a biosample plate storage cartridge 200 with itscover removed to show the storage slots for holding biosample plates, inaccordance with an embodiment of the invention. The biosample storagecartridge 200 comprises a plate holder 204 for holding a plurality ofbiosample plates 205. The plate holder 204 may be an integral part ofthe biosample storage cartridge 200 or a separate part that is attachedto the data storage cartridge 200 by fasteners or adhesive. The plateholder 204 may comprise a plurality of parallel slots 206 to hold thebiosample plates 205 in place and prevent the biosample plates 205 fromseparating from the plate holder 204 when the storage cartridge 200 isbeing moved. Movable door 202 is shown at the bottom corner of thecartridge 200.

In one embodiment, the width of the slots 206 is slightly larger thanthe thickness of the biosample plates 205 to snugly accommodate thebiosample plates 205 and firmly retain the biosample plates 205 in theslots 206 by friction. In one embodiment, the biosample plates 205 mayhave a thickness of 1.0 mm and the width of the slots 206 is slightlylarger than the thickness of the biosample plates. For example, for athickness of 1.0 mm for the biosample plates, the width of the slots maybe in the range of 1.05-1.2 mm. In an alternate embodiment, the materialcontaining slots 206 is elastic, such as a polymer or elastomer, and thewidth of slots 206 is slightly smaller, ranging from 0.90 mm to 1.0 mm.

The biosample plate storage cartridge 200 may include one or morecartridge memory 203 for storing data related to the biosample cartridge200, for example, the identification of the biological samples,biosample plates, analysis data on the biological samples, and relevantdates such as creation dates and analysis dates. The cartridge memory203 may be in communication with a wireless communication interface tosend information to and receive information from a remote transceiver,for example, in a tape library system that handles the biosample platestorage cartridge 200.

Although FIGS. 1-2 illustrate a biosample plate storage cartridge thathas the same form factor as a single reel magnetic tape cartridge, thebiosample storage cartridge may have the same form factor as a dual reelcartridge, such as the IBM 3570 cartridge. In a dual reel cartridge, themagnetic tape is fed between the two reels of the cartridge. Such abiosample plate storage cartridge may comprise a biosample plate holder204 in the space occupied by the two tape reels, as similarly describedwith reference to FIGS. 1-2.

FIG. 3 illustrates a cross-sectional side view of a biosample platestorage cartridge 300 with storage slots for holding the biosampleplates 305, in accordance with an embodiment of the invention. Thebiosample plates 305 are retained by the slots in the biosample storagecartridge 300 as described with reference to FIGS. 1-2. Cartridge memory303 is shown at a generally 45 degree angle, so that the memory may bewirelessly accessed by either the robotic picker in the automatedlibrary or the tape drive modified to perform bio-analysis.

FIG. 4 illustrates a block diagram of the functional components of amemory component 403 and a wireless communication interface 407, whichmay be part of a biosample storage cartridge 100, such as cartridgememories 103, 203, and/or 303. The memory component 403 may storeinformation about the biosample cartridge, biosample plates in thecartridge, and biosamples on the biosample plates. The memory component403 may comprise a nonvolatile memory 409, such as an electricallyerasable programmable read-only memory (EEPROM), a phase-change memory,flash memory, NOR memory, or a NAND memory arranged to operate in a lowpower environment. Memory component 403 also may comprise memoryprocessor 408, such as logic or a microprocessor chip, for example, anIntel Pentium™ chip arranged to operate in a low power environment, suchas a portable computer.

The memory processor 408 may have computer readable program codeembodied therein, including suitable security and encryption/decryptionalgorithms, and the logic for accessing and operating the memorycomponent 403. The memory component 403 may comprise a nonvolatilestorage 409, as is known to those of skill in the art. The nonvolatilestorage 409 may comprise a separate chip attached to the logic or memoryprocessor 408, or may comprise a portion of the same chip. The computerreadable program code may be stored in a nonvolatile internal memory ofthe processor 408 or in the nonvolatile memory 409, and loaded into theprocessor 408. Alternatively, the memory component 403 may be operatedby a control system or processor of an analytical system that uses thebiosample storage cartridge 100.

In the illustrated embodiment, the wireless communication interface 407may be a radio frequency (RF) wireless interface. An example of an RFwireless interface is described in U.S. Pat. No. 4,941,201. A highfrequency inductive wireless interface may also be employed, which is ofsufficiently high frequency so that it does not adversely affectmagnetic storage media that may be present in a tape library system thathandles the biosample storage cartridge. Examples of high frequencyinductive wireless interfaces are described in U.S. Pat. No. 4,650,981,U.S. Pat. No. 4,758,836, and U.S. Pat. No. 3,859,624.

The wireless communication interface 407 includes an antenna 410 forreceiving an RF signal from an RF interface of either a tape drivemodified to perform bio-analysis or a robotic picker that moves thebiosample plate storage cartridge 300 in a tape library system. Theantenna 410 may be positioned at an angle in the range of 30-60 degreesfor optimal reception of the RF signal, e.g., at 45 degrees as shown forthe cartridge memory 303 of FIG. 3. The antenna 410 may be a quarterwave antenna, a fractal antenna, or the inductor of aninductor-capacitor oscillator. A coupler 411 supplies the receivedsignal to a power conversion circuit 412 and to a data demodulator 413.The power conversion circuit 412 converts the received signal to a powercurrent, supplying the current on line 415 to all devices on thebiosample storage cartridge 300, including the memory component 404, thedata demodulator 413, and a data modulator 414. The received signal fromantenna 410 may be encoded. The data demodulator 413 receives theincoming coded signal from coupler 411 and demodulates the signal toprovide data signals to the memory component 404 and for writing tomemory 409. Data signals being read from memory 409 and memory component404 are provided to the data modulator 414 which encodes the signals fortransmission by coupler 411 and antenna 410 to an RF interface, whichmay be in either the robotic picker of the tape library system thathandles the biosample plate storage cartridge 300 or in the tape drivemodified to perform bio-analysis.

FIG. 5 illustrates an automated data storage tape library 500 that maybe used with the biosample plate storage cartridge shown in FIGS. 1-4,in accordance with an embodiment of the invention. The data storage tapelibrary 500 is an automated tape library that may include a number oftape drives 510 for reading and writing data on magnetic tape media,such as single-reel or two-reel magnetic tape cartridges. Examples ofthe library 500 include IBM TS3400™ and TS3500™ Tape Libraries. IBMTotalStorage™ 3494 Tape Libraries, and IBM 3952™ Tape Frames Model C20,which store magnetic tape cartridges and use IBM TS1130™ tape drives.Other examples of the library 500 include IBM TS3310™ and TS3100/3200™tape libraries which store magnetic tape cartridges and use IBM LTO(Linear Tape Open) tape drives. Tape drives modified to performbio-analysis accept cartridge 100, 200, 300 from the robotic picker,withdraw a biosample plate through door 202 of cartridge 200, andperform the bio-analysis.

A plurality of cartridges 520 are stored in banks or groups of cartridgestorage slots 521. Cartridges 520 may comprise tape media for datastorage, tape substrate for biosamples, or biosample plates 205 and 305for bio-analysis. Tape media may encompass a variety of media, such asthat contained in magnetic tape cartridges, magnetic tape cassettes, andoptical tape cartridges, in various formats. For universal reference toany of these types of media, the terms “tape media” or “media” are usedherein, and any of these types of containers are referred to as “tapecartridges” or “cartridges” herein. An access robot 523, including acartridge picker 522 and a bar code reader 524 mounted on the cartridgepicker 522, transports a selected cartridge 520 between a cartridgestorage slot 521 and a drive 510. Bar code reader 524 is mounteddirectly on picker 522 so that the library 500 can check the bar code oncartridge 520 before picking the cartridge and transporting it to adrive 510, storage slot 521, or import/export mail slot 526.

The automated tape library 500 further has a library controller 525which includes at least one microprocessor. The library controller 525may serve to provide an inventory of the cartridges 520 and to controlthe library 500. Typically, the library controller 525 has suitablememory and data storage capability to control the operation of thelibrary 500. The library controller 525 controls the actions of theaccess robot 523, cartridge picker 522, and bar code reader 524. Barcodereader 524 may read a barcode from cartridge 100, 200, or 300. Thelibrary controller 525 is interconnected through an interface to one ormore host processors, which provides commands requesting access to aparticular biosample plate, a tape media, or a cartridge in particularstorage slots. A host, either directly or through the librarycontroller, controls the actions of the drives 510 which either performdata 10 with tape media or, if suitably modified, perform bio-analysison the biosamples stored on plates 205 and 305. Commands for accessingdata or locations on the tape media and biosample plates, andinformation to be recorded on or to be read from selected tape media andbiosample plates, are transmitted between the drives 510 and the host.The library controller 525 is typically provided with a database forlocating the cartridges 520 in the appropriate storage slots 521 and formaintaining the cartridge inventory.

Library 500 also includes an import/export mail slot 526, which is aportal allowing cartridges 520 to be entered into or removed fromlibrary 500. Since cartridges 520 have a generally identical exteriordimensions regardless of whether they hold data tape or biosampleplates, cartridges 520 may enter library 500 through import/export mailslot 526, picked up by picker 522 and transported to eithercartridge-storage slot 521 or drives 510. Drives 510 would have a commoncartridge loader mechanism, whether the drive is a data drive or abio-analysis drive, because of cartridges 520 having identical exteriordimensions. Similarly picker 522 may pick cartridge 520 from a drive 510or cartridge-storage slot 521 and place it in import/export mail slot526 for removal from library 500. In an alternate embodiment, biosamplecartridges 520 are a different color from cartridges containing digitaldata, as well as containing information regarding their intended purposein memories 103, 203, and 303.

FIG. 6 illustrates a block diagram of the functional components in atape drive that may be used for analyzing a biosample and storingbiosample identification and analysis data, in accordance with anembodiment of the invention. The magnetic tape drive 600 comprises amemory interface 631 for reading information from and writinginformation to one or more of the cartridge memory 632 of the magnetictape cartridge 633, for example, in a contactless manner.

A read/write system is provided for reading and writing information tothe data storage media, such as magnetic tape, or nanoparticles on thebiosample plates 205 and 305, and may comprise a read/write head 634with a servo system for moving the head laterally of the magnetic tape635 or a biosample plate (not shown in FIG. 6). The servo system maycomprise a read/write and servo control 636 and a drive motor system 637which moves the magnetic tape 635 between the cartridge reel 638 and thetake up reel 639 and across the read/write head 634. The read/write andservo control 636 controls the operation of the drive motor system 637to move the magnetic tape 635 across the read/write head 634 at adesired velocity. The read/write and servo control 636 may determine thelocation of the read/write head 634 with respect to the magnetic tape635.

In one example, the read/write head 634 and read/write and servo control636 employ servo signals on the magnetic tape 635 to determine thelocation of the read/write head 634, and in another example, theread/write and servo control 636 employs at least one of the reels, suchas by means of a tachometer, to determine the location of the read/writehead 634 with respect to the magnetic tape 635. The read/write head 634and read/write and servo control 636 may comprise hardware elements andmay comprise any suitable form of logic, including a processor operatedby software, or microcode, or firmware, or may comprise hardware logic,or a combination. In an alternate embodiment, tape 635 is simply aflexible substrate, such as a MYLAR™ substrate, and biosamples arestored directly on this substrate and wound around reel 638 in cartridge633.

A control system 640 communicates with the memory interface 631, andcommunicates with the read/write system, e.g., at read/write and servocontrol 636. The control system 640 may comprise any suitable form oflogic, including a processor operated by software, or microcode, orfirmware, or may comprise hardware logic, or a combination thereof. Thecontrol system 640 typically communicates with one or more host systems641, and operates the data storage drive 600 in accordance with commandsoriginating at a host. Alternatively, the data storage drive 600 mayform part of a subsystem, such as a library, and may also receive andrespond to commands from the subsystem.

As illustrated, the data storage drive 600 provides information to acartridge memory 632 of the magnetic tape cartridge 633, and providesdata to the magnetic tape 635 of the magnetic tape cartridge 633.

In one embodiment, the data storage tape drive 600 may function as ananalytical system for scanning the biosample plates 205, 305 andanalyzing biological samples deposited on the biosample plates 205, 305to detect the presence of target antigens or substances. Themagneto-resistive (MR) heads of the read/write head 634 in data storagedrive 600 may act as the scanners for reading data from the biosamples.Write heads of read/write head 634 may magnetize nanoparticles used totag the biosamples which are subsequently read or detected by the MRheads. For example, an MR read/write head 634 may be used to detectmicro-organisms and antigens that are attached to magnetizednanoparticles.

An MR read-write head may scan a large number of biosamples deposited ona magnetic tape media as the MR read-write head traverses the tape mediaa high speed. The tape drive electronics may then process the signalsfrom the read-write MR head to detect the presence of targetmicro-organisms or antigens in the biosamples. Such as bio-assay processis described, for example, in the commonly-assigned US patentapplication entitled “Detection Of Analytes Via Nanoparticle-LabeledSubstances With Electromagnetic Read-Write Heads”, Ser. No. 12/888,388,herein incorporated by reference in its entirety.

FIG. 7 illustrates a block diagram of a representative computer system,some of which may be incorporated in a data storage tape library and acartridge memory to provide control and processing function, forproviding aspects of the disclosure. Data processing system 700 includesa processor 701, a memory 702, a persistent storage 703, a communicationinterface 704, an input/output unit 705, a display 706 and a system bus707. Computer programs are typically stored in persistent storage 703until they are needed for execution by an operating system running inmemory 702. Persistent storage 703 may comprise one or more hard diskdrives and multiple hard disk drives may be organized into a RAID, CD(Compact Disk) drives. DVD (Digital Versatile Disk) drives. BD (Blu-Ray)drives, SSD (Solid State Drives), and solid state memory. At that time,the programs are brought into the memory 702 so that they can bedirectly accessed by the processor 701. The processor 701 selects a partof memory 702 to read and/or write by using an address that theprocessor 701 gives to memory 702 along with a request to read and/orwrite. Usually, the reading and interpretation of an encoded instructionat an address causes the processor 701 to fetch a subsequentinstruction, either at a subsequent address or some other address. Theprocessor 701, memory 702, persistent storage 703, communicationinterface 704, input/output unit 705, and display 706 interface witheach other through the system bus 707.

The subject matter described above is provided by way of illustrationonly and should not be construed as limiting. Various modifications andsubstitutions of the described components and operations can be made bythose skilled in the art without departing from the spirit and scope ofthe present disclosure defined in the following claims, the scope ofwhich is to be accorded the broadest interpretation so as to encompasssuch modifications and equivalent structures.

What is claimed is:
 1. A computer-implemented method of using abiosample storage cartridge comprising: performing bioanalysis on one ormore biosamples in one or more biosample plates in a holder of abiosample storage cartridge, the biosample storage cartridge having anenclosure having a same form factor as a data tape cartridge that isconfigured for use in an automated tape library, the holder beingdisposed in the enclosure, wherein the holder comprises a plurality ofslots, each slot being configured to receive a biosample plate.
 2. Themethod as recited in claim 1, comprising receiving the one or morebiosample plates in the slots.
 3. The method as recited in claim 1,comprising retrieving the cartridge from the automated tape library. 4.The method as recited in claim 3, the retrieving being performed using apicker of an access robot of the automated tape library.
 5. The methodas recited in claim 1, comprising delivering the cartridge to abioanalysis drive of the automated tape library.
 6. The method asrecited in claim 1, comprising magnetizing at least some nanoparticlesto which the one or more biosamples are attached.
 7. The method asrecited in claim 6, wherein the magnetizing is performed using aread/write head of a bioanalysis drive of the automated tape library. 8.The method as recited in claim 1, the bioanalysis comprising detecting apresence of the one or more biosamples in the one or more biosampleplates.
 9. The method as recited in claim 8, wherein the detecting isperformed using a read/write head of a bioanalysis drive of theautomated tape library.
 10. The method as recited in claim 1, whereinthe bioanalysis comprises detecting presence of one or more of: a targetantigen and a target microorganism in one of the biosample plates.
 11. Acomputer program product for using a biosample storage cartridge, thecomputer program product comprising a computer readable storage mediumhaving program instructions embodied therewith, the program instructionsexecutable by an analytical system to cause the analytical system to:perform, by the analytical system, bioanalysis on one or more biosamplesin one or more biosample plates in a holder of a biosample storagecartridge, the biosample storage cartridge having an enclosure having asame form factor as a data tape cartridge that is configured for use inan automated tape library, the holder being disposed in the enclosure,wherein the holder comprises a plurality of slots, each slot beingconfigured to receive a biosample plate.
 12. The computer programproduct as recited in claim 11, comprising program instructionsconfigured to cause the analytical system to receive the one or morebiosample plates in the slots.
 13. The computer program product asrecited in claim 11, the computer program product comprising programinstructions configured to cause the analytical system to retrieve thecartridge from the automated tape library.
 14. The computer programproduct as recited in claim 11, comprising program instructionsconfigured to cause the analytical system to retrieve the cartridgeusing a picker of an access robot of the automated tape library.
 15. Thecomputer program product as recited in claim 11, comprising programinstructions configured to cause the analytical system to deliver thecartridge to a bioanalysis drive of the automated tape library.
 16. Thecomputer program product as recited in claim 11, comprising programinstructions configured to cause the analytical system to magnetize atleast some nanoparticles to which the one or more biosamples areattached.
 17. The computer program product as recited in claim 16,wherein the magnetizing is performed using a read/write head of abioanalysis drive of the analytical system.
 18. The computer programproduct as recited in claim 11, the program instructions configured tocause the analytical system to perform the bioanalysis comprisingprogram instructions configured to cause the analytical system to detecta presence of the one or more biosamples in the one or more biosampleplates.
 19. The computer program product as recited in claim 11, whereinthe detecting is performed using a read/write head of the analyticalsystem.
 20. The computer program product as recited in claim 11, whereinthe bioanalysis comprises detecting a presence of one or more of: atarget antigen and a target microorganism in one of the biosampleplates.